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By injecting the dextrose solution into the ligamentous attachments of the AC joint, prolotherapy stimulates the growth of new collagen and reinforces the structural integrity of the joint

It points to B vitamins and magnesium as the deficiencies worth investigating when discomfort does not settle, alongside dehydration and pre-existing musculoskeletal conditions

Sixty patients aged 65 and older were randomly assigned to either a loading dose regimen (daily administration for 14 days followed by weekly doses) or a regimen without a loading dose (administration every 3 days) over 90 days

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It describes the current suitable population as people with type 2 diabetes, prediabetes, or obesity with cardiovascular risk factors or comorbidities