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AOD9604 did not stimulate the production of IGF-1 in any of the systems studied, and elicits its fat-reducing effects without inducing insulin resistance a key pharmacological distinction from intact hGH that makes it a uniquely clean research tool for studying lipolytic mechanisms in isolation

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The retatrutide figure is the highest reported, but it comes from a shorter Phase 2 study and has not yet been confirmed at Phase 3 scale

In some embodiments, auris formulations or compositions described herein are controlled release formulations, and are administered at reduced dosing frequency compared to the current standard of care

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