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Moreover, Engrailed-2 is expressed upon activation of the Wnt signaling pathway

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24 There have been reports that phenolics also inhibit the expression of both HMG-CoA reductase, involved in the regulation of cholesterol biosynthesis, and sterol regulatory element-binding protein-2, which triggers HMG-CoA for cholesterol biosynthesis in the liver

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The study documented two key findings: a positive correlation between ammonia and S100B levels