Low concentrations of ascorbate, glutathione, and superoxide dismutase are the most prevalent antioxidant deficits during the pathogenic process of diabetes
An acidic environment may activate GPER signaling by affecting the cell membrane potential and ion channel activity, thereby enhancing the metabolic adaptability and survival capacity of tumor cells [232, 233]
doi: 10.1016/j.plipres.2018.09.002 79 AnthonymuthuTSKennyEMShrivastavaITyurinaYYHierZETingH-Cet al
In erythroleukemia K562 cells, in addition to the above identified NRF2 binding ARE motif, there is also a strong association of active histone codes (such as H3K4Me3, H3K9Ac, H3K27Ac, H3K79Me2) upstream of the transcription start site (Supplementary Fig
Glutathione may help promote brighter and more even-toned skin by reducing oxidative stress and supporting healthy skin cells