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doi:10.1101/2023.11.16.567423 Tucker M, Liao GY, Park JY, et al
Solid-phase peptide synthesis dominates the industry, but newer recombinant production methods can reduce costs for certain peptides
The NYT also named the reason drug companies never ran trials on most of these: theyre easy to manufacture and dont clearly target a disease
[3][4] Research has examined T4 (and its TB-500 fragment) in the context of: Cell migration at wound margins Corneal and dermal wound healing in preclinical models [5] Cardiac repair following ischemic injury an area of active investigation Hair follicle stem cell migration Anti-inflammatory modulation The active 17-amino-acid sequence is well-characterized, and synthetic TB-500 is widely used in research as a stable proxy for full-length T4 protein
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