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a , Dose-response curves showing relative cell number after 72 h of treatment of HCC-1806 cells with vincristine (0-5 nM) in the presence of the MRP1 inhibitor MK-571 (0-15 M) (n = 8 technical replicates from one experiment)

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In the CI-AKI mouse model, significant attenuation of renal tubular cell apoptosis by TMP was observed, potentially mediated by suppressing the p38 MAPK and FoxO1 pathways (Gong et al., 2013)

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