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however, senescent cells infamously secrete high levels of pro-inflammatory cytokines, chemokines, and extracellular matrix-degrading proteins that negatively impact the extracellular environment and induce spread of senescence to non-senescent cells (2932)

10.1016/j.brainresbull.2020.05.013 119 LiJ.YuH.YangC.MaT.DaiY

By performing a further careful incision, taking care not to damage the biceps femoris muscle, tensor fasciae latae, and the fascia lata itself, as well as the associated blood vessels of the region, the anatomical attachments of all four heads of the quadriceps muscles were identified and sharply dissected at their anatomical insertions with a surgical knife

Notably, GSH supplementation rescued the levels of downstream cysteine-related products (Extended Data Fig