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It is prescribed for chronic weight management in adults who are overweight or obese and have at least one weight-related health condition, such as high blood pressure, type 2 diabetes, or high cholesterol

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Stabilized GHRH (Tesamorelin) Tesamorelin is a structurally stabilized GHRH analog with a longer half-life and stronger effect on visceral adipose tissue than older GHRH peptides

doi: 10.1002/cne.23355 2

ZSF1 obese rats exhibited these features, displaying progressive diastolic dysfunction (increased E/e ratio) over the 16 weeks, elevated left ventricular end-diastolic pressure (LVEDP), increased systemic blood pressure, and marked cardiac interstitial fibrosis