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Given the aggressive nature of MPNST and its high rate of local recurrence and metastasis, early diagnosis and coordinated care at specialized sarcoma centers are essential (Widemann & Italiano, 2018)
Fatty, greasy foods and large meals can bring on bouts of nausea and vomiting, Jay explained
Both ATP competitive and ATP non-competitive tyrosine kinase inhibitors (TKI) were developed towards IGF-1R (Table 1) and showed remarkable efficacy in pre-clinical studies
Patients should be reassured that gastrointestinal symptoms often improve with continued therapy as tolerance develops
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