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STEP 4 showed that discontinuing semaglutide led to significant weight regain, confirming that the drug actively maintains weight loss while being used

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She noted that the new findings align with what weve found in similar studies on the association of GLP-1 medications with lower risk of suicidal ideation. Its still important, though, for clinicians to assess mental health and suicidal thoughts among adolescents taking these medications, Volkow wrote in an e-mail, so that proper support can be given to those at risk and harmful health outcomes can be prevented. Adolescence can be a particularly difficult time for mental health, she added

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Once we confirm a deficiency, we'll work with you to figure out what's causing it