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More serious but less common safety considerations observed across this drug class include a potential risk of pancreatitis, gallbladder-related conditions (such as gallstones/cholelithiasis), and based on animal studies a theoretical concern regarding thyroid C-cell tumours, though this has not been confirmed in human trials

Wang-Evers, M.J

To provide better access to these products, PBMs should remove step therapy requirements from both drugs so patients and prescribers have easier access and increase use of SGLT2 therapies, which are generally less expensive but efficacious

It is recommended to take an hour before doing the exercise

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