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I., Khavinson, V

In addition to reviewing numerous scientific studies, we also consulted with experienced clinicians knowledgeable about peptides to gain further insight

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When You Might Need Higher B12 Doses While the standard RNI of 1.5 mcg per day suffices for most healthy adults, certain medical conditions, dietary patterns, and medications can substantially increase B12 requirements or impair absorption, necessitating higher therapeutic doses under medical supervision

The absorption process is significantly hindered in conditions such as pernicious anemia, Crohns disease, celiac disease, and following ileal surgical resection, all of which can impair B12 absorption and contribute to suboptimal supplementation outcomes