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Autistic symptom changes were not evaluated as part of the study, but children in both groups showed improvement in cysteine, plasma sulfate, and whole-blood glutathione levels

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Reported data show clinically meaningful HbA1c reductions and weight loss exceeding semaglutide monotherapy in the same population, supporting continued Phase 3 investigation

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Sevoflurane offers protection to the glycocalyx, with patients in the sevoflurane group exhibiting significantly reduced concentrations of glycocalyx markers in the blood (such as SDC-1, HS, and HA) and enzymes responsible for glycocalyx degradation (such as MMP-9 and cathepsin-B), compared to the control drug propofol [128]