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What people refer to as adrenal fatigue can actually be due to: HPA Axis Dysregulation (HPA-D): where the brain and adrenal communication becomes dysregulated Cortisol receptor resistance: where the cell receptors become unresponsive to the signals of cortisol Increased enzyme activity: where cortisol is converted to its inactive form, cortisone Your body has these mechanisms in place to keep you alive and protect you from the damage of excess cortisol

10.1007/s10858-008-9244-4

Merkuriuz Lek, 11:247-251 (2001)

Engineering bacteria-activated multifunctionalized hydrogel for promoting diabetic wound healing