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The mean (SD) free carnitine concentration was 45.38 12.61 mol/L in the patient group, whereas it was 41.54 9.85 mol/L in the healthy control group, and the difference between the 2 groups generated a P value of 0.049

The resultant opening of voltage-dependent L-type Ca 2+ channels increases the intracellular concentration of Ca 2+ , which also acts as a second messenger, augmenting neurotransmitter release [33]

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