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Structural gut damage (ulcers, mucosal erosion): BPC-157 is the choice

The most common complaints were nausea (55% versus 12.6% with placebo), constipation (30.7% versus 11.6%), and vomiting (26.1% versus 4.1%)

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Specifically, the synergistic action of metformin and simvastatin reshaped glioma metabolism, curbed malignant proliferation, promoted apoptosis, and demonstrated superior anti-tumor effects both in vitro and in vivo compared to individual administration of metformin or simvastatin

Reprod Biol Endocrinol 22(1):93 Lopez-Yaez Blanco A, Daz-Lpez KM, Vilchis-Gil J, Diaz-Garcia H, Gomez-Lopez J, Medina-Bravo P et al (2022) Diet and maternal obesity are associated with increased oxidative stress in newborns: a cross-sectional study