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Evidence for involvement of furin in cleavage and activation of diphtheria toxin

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Thus, it is not surprising that GSH (or the [GSH]/[GSSG] ratio) plays a key role in many diseases including cancer, inflammation, Alzheimer's disease, Parkinson's disease, sickle cell anemia, liver disease, cystic fibrosis, AIDS, heart attack, stroke, and diabetes [4, 6] as well as in aging [79]

PLoS One , 16 (11), e0259502

A comparison of the two complexes (Tirzepatide bound to GLP-1R vs GIPR) shows that several of the same amino acids of the peptide interact with corresponding amino acids in the GLP-1 with GLP-1R