These activated adipose tissue macrophages secrete cytokines that further exacerbate the pro-inflammatory state
Frias JP, Deenadayalan S, Erichsen L, et al
As shown in Section Riboflavin Ameliorates Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation, riboflavin has antioxidant properties and upregulates antioxidant enzymes especially SOD, also, supplementation with riboflavin will elevate the intra-mitochondrial FAD levels compensating for the decline in the capacity to assemble of dysfunctional mitochondrial complexes
Accessed 15 Feb 2024 Zhang W, Wang L, Xiang F, Qin W, Jiang W (2020) Vegetation Dynamics and the Relations with Climate Change at Multiple Time Scales in the Yangtze River and Yellow River Basin, China
This suggests that eating foods high in sulfur and sulfur-containing amino acids could also help glutathione production, as a lack of cysteine is thought to be its main bottleneck [41]