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Stimulating the sir2-spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome

Some people report better sleep quality, healthier-looking skin and nails, and improved metabolism

Instead, it works through a different mechanism: gabapentin reduces abnormal electrical activity in damaged or sensitized nerves, thereby decreasing pain perception and the neural drive to move the legs

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But the practical implication is that once a clinician approves you, you've committed to the medication cost regardless of whether you change your mind