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[171] "Gut-liver axis targets" that either change a person's microbiome, or act on bile acids [170] Anti-fibrotic drugs, [170] such as fibroblast growth factor analogues, which have largely not met their endpoints [171] Other treatments such as farnesoid X receptor (FXR) agonists, peroxisome proliferator-activated receptor (PPAR) agonists, and ASK1 (apoptosis signal-regulating kinase 1) inhibitors may improve MASFLD by multiple mechanisms simultaneously

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Do not use in dogs with known tympanic membrane perforation (see Precautions)