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The collagen synthesis mechanisms involve MAPK/ERK pathway activation, which upregulates collagen gene expression at the genetic level

Yes, under supervision

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In addition, absolute quantification was performed in 116 metabolites including glycolytic and TCA cycle intermediates, amino acids, and nucleic acids

These results suggest that ketamine-ethanol combination induces neurotoxicity by triggering oxidative stress and apoptosis in a time-dependent manner prior to cell death, increasing the risk for neuronal damage compared to individual drug exposure