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A 2018 review article published in the World Journal of Mens Health noted that decreased secretion of DHEA may be a risk factor for erectile dysfunction

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43,356 Moreover, long-term follow up data from patients with type 1 and type 2 diabetes have confirmed that hyperglycemia is a risk factor for CVD

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The rational to target PD-1/PD-L1 axis in senescence is evident and the large panel of drugs approved to target this pathway will probably accelerate the development of this strategy