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When P-15 is added in scaffold material, it results in a significantly higher gene expression of alkaline phosphatase (ALP), BMP-2 and BMP-7 [235]

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However, 1-h gastric emptying was 23% lower than placebo with liraglutide 3.0 mg ( P =0.007), and a nonsignificant 13% lower than placebo with liraglutide 1.8 mg ( P =0.14)

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Both exogenous and endogenous PYY have been shown to be degraded in vivo in animal and clinical studies