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These include: Deep cracks and scales on dry skin Yellow or orange color to the palms or soles of the feet Reddening of the palms Flushing in the face Darker skin in the mouth, gums, or creases of the palms Reddish spots on the skin Swollen face Wounds that are slow to heal Certain Medications Marks on the skin that are caused by medications are referred to as drug-induced pigmentation

Lipohypertrophy refers to the buildup of fatty lumps under the skin from repeated injections in the same area