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Notwithstanding about the promising mechanisms of action, translation to patients is limited by bioavailability and pharmacokinetic issues, inter-subject variability and possible interactions with other chemotherapeutic agents or endocrine therapies highlighting the need for well-conducted randomised controlled trials and PKPD studies (248)

Structure-based modelling in reproductive toxicology: (Q)SARs for the placental barrier

For patients who are naturally B12 deficient, more frequent injections about once a month may be ideal

As such, it is advised that patients facing this condition seek professional healthcare assistance from dermatologists or trichologists in Bangalore since they would be able to provide suitable treatment plans depending upon the patients medical history