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TJ complexes are primarily composed of transmembrane proteins including occludins, junctional adhesion molecules, and claudin family members that function collectively to form pores with selective permeability to ions and molecules (Brenchley and Douek 2012

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Combining glucagon-like peptide 1 receptor agonists and sodium-glucose cotransporter 2 inhibitors to target multiple organ defects in type 2 diabetes

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