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in Cell Metabolism note that SIRT1 activation improves mitochondrial efficiency and promotes a shift toward lipid utilization for energy, which can be especially beneficial in endurance and fat-loss settings (Price et al., Cell Metabolism )

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However, if you've lost significant weight, your overall metabolic rate may be lower than before starting (smaller body = lower baseline metabolism)

Reduced body fat, particularly in stubborn areas, often becomes visible

S., Thompson, C