With larger than recommended doses, a person might experience nausea, vomiting, diarrhea, stomach painsimilar abdominal and intestinal issues that can occur with high doses of BCAAs, Creatine or Beta Alanine, etc
In patients with mutations in the C9ORF72 gene, the production of harmful dipeptide repeat proteins further disrupts communication between the nucleus and cytoplasm, impairing cell function
However, supplements aren't tested by the FDA before they're sold, so use caution when you buy and use peptide supplements
Experts say the positive effects may have to do with the drugs effects on dopamine
This raises an important clinical question: if cardiometabolic risk is present, should GLP-1 therapy be considered even in patients who do not meet traditional BMI thresholds