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Pentadecapeptides, including BPC-157, have demonstrated protective effects on the gastrointestinal mucosa and may indirectly enhance musculoskeletal recovery by reducing systemic inflammation and optimizing nutrient absorption

This process is primarily executed by members of the gasdermin family, most notably gasdermin D (GSDMD), which is activated by inflammatory caspases in both canonical and non-canonical inflammasome pathways 51

These distinctions matter when research outcomes depend on isolating a single variable

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