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Biological Psychiatry prepint de Pins B et al (2019) Conditional BDNF delivery from astrocytes rescues memory deficits, spine density, and synaptic properties in the 5xFAD mouse model of Alzheimer disease

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[60] In some cases, the patient can produce an immune response against GH

Benefits have been observed to persist after treatment stops, suggesting initiated repair processes continue independently

Foundational mouse study (Baar et al., 2017, Cell) Designed FOXO4-DRI and showed selective senescent-cell clearance, with restored fitness, fur density, and kidney function in aged and chemotherapy-treated mice