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When combined with endogenous antioxidants like reduced glutathione and dietary antioxidants like ascorbic acid, UA provides antioxidant defences to the epithelial lining fluid of the airways, protecting against respiratory illnesses [127]

Similarly, rats harboring the same DMT1 G185R mutation show reduced susceptibility to 6-hydroxydopamine (6-OHDA)-induced neurotoxicity, with 42.6% dopaminergic neuron loss versus 61.6% in wild-type and 65.9% in heterozygous animals ( Lysosomes serve as dynamic iron reservoirs and key regulators of cellular iron homeostasis

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