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Inhibitors reported herein are effective against all stages of schistosome development, decrease egg production, improve liver pathology, and are orally bioavailable

doi: 10.1021/acs.molpharmaceut.9b00157 36 Rahmani EliatoTSmithJTTianZKimESHwangWAndamCPet al

This is in contrast to our earlier results in the absence of salicylamine (Figures 3d and e), suggesting that the ability to form -KA-DAT adducts is necessary for AA to impair DAT function