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The History and FDA Approval of Trulicity Trulicity (generic name: dulaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist developed by Eli Lilly

Those formats, however, raise solubility, stability, taste, and mouthfeel challenges

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For instance, PDAPEG and PDAPEGTPP nanoparticles (where TPP denotes triphenylphosphine) facilitate targeted delivery to the nucleus and mitochondria, enhancing drug accumulation in cancer cells and overcoming drug resistance (Li et al., 2017)