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It is not approved for human or animal use and must not be administered outside controlled in-vitro research environments

Therefore, it is important to investigate the mechanism of TMAO exacerbating kidney disease through activation of the inflammatory response, which can help TMAO become an effective target

However, ferroptosis may be a double-edged sword for tumor cells, which can enhance not only the function of anti-tumor immune cells but also the tumor-promoting response of immunosuppressive cells under certain circumstances (158)

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Smedman A, Basu S, Jovinge S, Fredrikson GN, Vessby B