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in 2022 at 39.9% but has ticked down to 36.4%, according to the latest data based on self-reported height and weight

The regulatory environment for compounded GLP-1 programs is subject to active FDA rulemaking with a June 29, 2026 public comment deadline

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However, because retatrutide remains investigational, its benefits must be interpreted alongside its evolving safety profile, dose-related side effects, and the need for ongoing clinical monitoring