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IGF-I deficiency is associated with growth hormone insensitivity syndrome (GHIS) also called Laron syndrome, liver cirrhosis, age-related cardiovascular and neurological diseases, and intrauterine growth restriction

Systemic steroids are more likely to cause weight changes, but inhaled corticosteroids generally have minimal impact on weight when used at recommended doses

Microneedling for enhanced absorption and wound healing stimulus

This benefit makes it a popular choice