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Reports have shown a lower incidence of anxiety and depression in GLP-1 analog users [like semaglutide] compared with nonusers, possibly due to anti-inflammatory effects on neuroinflammation and reduced concern about weight gain, says Roshani Sanghani, MD, an endocrinologist in private practice who sees patients via telemedicine

For Capsule Convenience and Stability S-acetyl glutathione may be considered when a stable capsule format improves tolerance, travel convenience or adherence

1Pharmacokinetic and pharmacodynamic studies with CJC-1295, a long-acting growth hormone releasing peptidePubMed / Journal of Clinical Endocrinology & Metabolism 2006 2Ipamorelin, the first selective growth hormone secretagoguePubMed / European Journal of Endocrinology 2001

PMID: 51 GongB.YaoZ.ZhouC.WangW.SunL.HanJ

An analysis of the FDA's adverse event database found that semaglutide (Ozempic) had the highest odds ratio for reporting constipation among GLP-1 medications