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doi:10.1016/j.biochi.2012.10.008 Prasath GS, Subramanian SP (2013) Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats

While genetics does not predict exact tapering response, certain variants correlate with stronger hunger signals post-discontinuation, informing more cautious protocols

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In human muscle cell studies 4 , IGF-1 directly increased myotube nuclei, fusion index, and myosin heavy chain content, all key indicators of muscle growth