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No definitive research establishes optimal timing, leaving this decision to individual preference and circumstance

Endocrinology 133: 57-62, 1993

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doi: 10.1002/j.1460-2075.1991.tb07947.x [DOI] [PMC free article] [PubMed] [Google Scholar] 68.Davis PJ, Goglia F, Leonard JL

We additionally assessed inflammatory involvement in peri-pancreatic adipose tissue, a visceral fat depot enriched in leukocytes and implicated as a source of mediators affecting -cell dysfunction 23,24