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Direct contact with the gut lining during alcohol exposure provides localized protection exactly where damage occurs
Gene expression analysis in ARPE-19 cells was conducted by amplifying the following genes: SOD2 (protein name: superoxide dismutase 2, mitochondrial), CAT (protein name: catalase), HMOX1 (protein name: heme oxygenase 1), SNAL1 (protein name: Snail Family Transcriptional Repressor 1), ZEB1 (protein name: Zinc finger E-box-binding homeobox 1), TWIST1 (protein name: Twist Family BHLH Transcription Factor 1), VIM (protein name: Vimentin), FN1 (protein name: Fibronectin 1), ACTA2 (protein name: actin alpha 2, smooth muscle) and GAPDH (protein name: glyceraldehyde-3-phosphate dehydrogenase)
10.1136/bmj.i4919 [DOI] [PMC free article] [PubMed] 22.Higgins JPT, Jackson D, Barrett JK et al (2012) Consistency and inconsistency in network metaanalysis: concepts and models for multiarm studies
This combination is studied for synergistic effects on tissue repair, angiogenesis, cell migration, inflammation modulation, and regenerative biology in preclinical models