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On the other hand, an increased distribution of MDM2 to the cell nucleus to interact with p53 may indirectly increase the expression of IGF-1R since lesser cytoplasmic MDM2 will be available to ubiquitinate and degrade the receptor
Wnt modulates the production of inflammatory cytokines and NF-B signaling and bridges innate and adaptive immune pathways (61)
doi: 10.1080/10715762.2018.1505044
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