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Comment: Commenters stated that the proposals would create distortions in the MS-DRG relative weights and that CMS has not modelled the impacts of or otherwise accounted for these distortions in the proposed policy

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AOD 9604 Powder COA The molecular structure and chemical properties of AOD 9604 Molecular Structure AOD The chemical name of 9604 is L-phenylalanine-L-tyrosyl-L-L-leucyl-L-L-arginyl-L-Isoleucyl-L-valinyl-L-Glutamide-L-Cysteinyl-L-arginyl-L-seramide-L-valinyl-L - -glutamide-glycyryl-L-Seramide-L-cysteinylglycyryl-L (cyclic disulfide bonds are connected at positions 7-14 It has the molecular formula C78H123N23O23S2 and a molecular weight of 1815.1 Da

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A drug that produces greater average weight loss may not deliver better outcomes if it is less well tolerated by a specific patient