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The FDA has not evaluated it for safety or efficacy in humans

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Preclinical studies have not identified toxic doses or lethal doses for BPC-157, and researchers reported no teratogenic, genotoxic, anaphylactic, or local toxic effects

Furthermore, a nutritional study has shown that prolonged periods of dietary copper deficiency can lead to elevated cholesterol, blood pressure, homocysteine, isoprostane and uric acid levels

In inflammatory bowel disease models, BPC-157 reduced the severity of experimentally induced colitis in rats when administered either intraperitoneally or intraluminally, suggesting activity through both systemic and local routes (Sikiric et al., 1993