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15 However, a key function of the claudin-2 protein is also to serve as a paracellular transporter for Na + and Ca 2+ ions, which may compete to pass through the claudin-2 pores

Saikosaponin D inhibits nasal inflammation by decreasing the levels of TNF-, IL-4, IL-5, IL-17, GATA-3, and RORt in AR mice [171]

GHK-Cu stimulates the growth of blood vessels and nerves, while also enhancing collagen presence, glycosaminoglycan synthesis, and elastin levels in both the body and the skin

In AD, GLP-1R attenuates the pathological features of AD through mechanisms such as anti-inflammatory effects, the reduction in amyloid-beta (A) deposition, the promotion of A clearance, and improvements in insulin signaling

However, this senescent cell function wanes with ageing, not only causing dysfunction in body tissues but also triggering inflammation and the formation of cancer cells [140]