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(1981) reported that their laboratory had found that incubation of cyanocobalamin for 30 minutes at body temperature and pH 7 with 500 mg of vitamin C resulted in the degradation of 1/3 of the cyanocobalamin

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Handle in accordance with applicable laboratory safety guidelines

Hydroxocobalamin is preferred because it has a longer half-life and is retained in the body more effectively than cyanocobalamin (which is mainly available as oral supplements in the UK)

Novel pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty-acid metabolism and mitochondrial function