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However, despite their significant quality of life improvements, they can be accompanied by significant gastrointestinal side effects, including nausea, vomiting, abdominal pain, diarrhea, fatigue, and weight loss 16

New or Worsening Food Intolerances: Sealing the tight junctions prevents large, undigested food proteins from entering the bloodstream, which reduces the immune system's hyper-reactive antibody response to previously tolerated foods

In addition, the inflammatory factor of smoking was found to augment EAAT3 expression in both human and murine experimental models

When these nutrients are missing, the nails become weak, peel easily, or grow slowly

J Pathol (2015) 236(4):51730