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It is not known if Ozempic will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. A 2023 study found that using these drugs for one to three years was associated with a 58 percent increased risk of all thyroid cancers, and a 78 percent increased risk of medullary thyroid cancer

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This structural modification improves bioavailability in research models but also makes the molecule more susceptible to denaturation under improper storage conditions than endogenous IGF-1

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