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Although men may produce testosterone through the luteinizing hormone (LH) pathway in the testes (175), this production may be lower than in healthy individuals due to the reduction of available DHEA and may favor inflammatory responses

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Hermel et al., 2021) as adjunct treatments for SARS-CoV-2 infection needs to be further emphasized

Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH 2-terminal kinase and up-regulation of death receptors

To sum up, gut microbiota plays a very important part in the bioavailability of (poly)phenols and ultimately, in their biological activity