average dose of semaglutide to lose weight Loss Dosage Chart I CGM Semaglutide dosing guidelines for 2026

Last reviewed: June 7, 2026 Last updated: June 7, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

PlexusDx maps 14 pathways, 49 peptides, and 150+ genetic insights so you and your provider can see how your genes relate to these pathways

The maximum target maintenance dose is 2.4 mg weekly for weight management

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The GLP-1 mechanism works through the same hormonal pathways your body already uses to regulate hunger, which is why the appetite reduction tends to feel natural rather than forced