does nadph reduce glutathione Reductase - an overview Diagram of the Pentose Phosphate

doi: 10.1016/j.cell.2021.06.019 29

Indeed, recommendations to incorporate the use of imaging and fluid biomarkers as part of the diagnosis on a broader scale has been recommended by newer National Institute on Aging and the Alzheimers Association working groups [65, 98, 99] would help to characterize endogenous antioxidant changes in early stages of disease and offer insight into GSHs potential as a therapeutic target

Rouzer, C

Collectively, to better understand the therapeutic potential of NADPH metabolism, more preclinical and clinical studies should be implemented to address these difficulties, and combined approaches with immunotherapy and/or chemotherapeutics should be pursued as the best strategies because of their synergistic effects

Glutathione is a very powerful anti-oxidant